Large doses (three or maybe more instances the equivalent productive human dose) of morphine, meperidine, and atropine amplified the depth and extended the period of anesthesia made by an ordinary anesthetizing dose of ketamine hydrochloride in Rhesus monkeys. Ketamine presents a generally hepatic metabolism and its big metabolite is norketamine. https://milogvjue.tinyblogging.com/facts-about-what-is-the-brand-name-for-ketamine-revealed-74443118