Mammalian prions. the pathogens that cause transmissible spongiform encephalopathies. propagate by self-perpetuating the structural information stored in the abnormally folded. aggregated conformer (PrPSc) of the host-encoded prion protein (PrPC). https://ashleyshomestores.shop/product-category/zero-wall-wide-seat-recliner-with-power/