Critically ill clients: Nitrous oxide inactivates methionine synthase by way of oxidation of the cobalt in vitamin B12 and will bring about megaloblastic anemia. This enzyme is important for vitamin B12 and folate metabolism and performs a role in DNA and RNA synthesis as well as synthesis of other substances. https://johnnyxoeuj.wonderkingwiki.com/1767276/the_fact_about_nitrous_oxide_canisters_that_no_one_is_suggesting